Quick detail:
Name:Doxorubicin hydrochloride
MW: 579.9802
CAS: 25316-40-9
EINECS. 246-818-3
Appearance: Microstrip orange-red crystalline powder, no impurity
Content: ≥ 98%
pH: 4-5.5
Moisture: <4.0%
Policy: 100% Re-Shipping
Description:
Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.
Specification:
Melting Point: 216 °C (dec.)(lit.)
Boiling Point: 810.3 °C at 760 mmHg
Flash Point: 443.8 °C
HS Code:3002909091
pH: 4-5.5
Moisture: <4.0%
Impurities: 0.55
Storage: Airtight container, protected from light
Appearance: Orange powder
Application:
1) Hodgkin's disease and lymphosarcoma, reticulum cell sarcoma.
2) undifferentiated small cell and non-small cell lung cancer, breast cancer.
3) acute lymphoblastic and myeloid leukemia.
4) osteosarcoma and soft tissue sarcoma.
5) ovarian cancer, testicular cancer, bladder cancer, . Wilms cancer, prostate cancer, thyroid cancer, neuroblastoma cancer, esophageal cancer, stomach cancer, liver cancer, cervical cancer and head and neck cancer. Multiple myeloma, pancreatic cancer, endometrial cancer and brain tumors can also be applied.
COA:
|
Product name |
Dexamethasone-17-acetate | |
| Appearance | White crystalline powder | |
| Chromatographic purity |
Any individual impurity not more than 1.0%
Total impurities not more than 2.0% |
0.3%
1.0% |
| Loss on drying | Not more than 0.5% | 0.3% |
| Residue on ignition | Not more than 0.2% | 0.07% |
| Residual solvents |
Methanol≤3000ppm
Methylene Chloride≤600ppm Chloroform≤60ppm Tetrahydrofuran≤720ppm |
335ppm
Not detect out Not detect out Not detect out |
| Assay | Between 97.0% and 102.0% | 98.9% |
| Micronixation | 90% not more than 10 microns |
90% not more than 10
aicrons |
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