| CAS25316-40-9 Doxorubicin HCl | |
| Identification | |
| Name | Doxorubicin hydrochloride |
| Other names |
ADRIACIN;ADRIBLASTINA;ADRIBLASTINAHYDROCHLORIDE;ADRIAMYCINHCL;
ADRIAMYCINHYDROCHLORIDE;(8s-cis)-10-[(3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy]-7Chemicalbook,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dionehydrochloride;14-HYDROXYDAUNOMYCINHCL;14-HYDROXYDAUNOMYCINHYDROCHLORIDE |
| CAS number | 25316-40-9 |
| Molecular Formula | C27H30ClNO11 |
| Molecular Weight | 579.98 |
| EINECS | 246-818-3 |
| Chemical and Physical Properties | |
| Appearance | Orange to dark red |
| Melting point | 216 °C |
| Quality standard | CP/USP |
| Application | |
| Drug Indication/Application/Use | Adriamycin is an anti-tumour antibiotic that inhibits the synthesis of RNA and DNA, with the strongest inhibitory effect on RNA, and has a broad spectrum of anti-tumour activity. |
| Formulations/Preparations | Oral Tablet |
What is Doxorubicin hydrochloride?
Doxorubicin is a chemotherapy medication used to treat cancer. This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. It is often used together with other chemotherapy agents.
Doxorubicin is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.
| Fast | Suitable | |
| DHL / FEDEX / EMS | 3-7 days | 50 kg |
| By Air | 5-15 days | > 50kg |
| By Sea | 10-45 days | > 1000kg |