Heparin Sodium Powder Prevents Blood Embolism CAS: 9041-08-1 Anticoagulant Drugs

Quality Requirement
Strictly Quality Control
Market
Worldwide
Resource
Natural
Grade
Pharmaceutical Grade
MW
887.04
Service
Welcome to Visit Us
Test Method
HPLC
Storage
Store Cool Dry Place
MOQ
1kg
Appearance
White Powder
Shelf Life
2 Years
CAS No
9041-08-1
Transport Package
Foil Bag
Specification
99%
Trademark
Xi′an Frazer Biotech Co., Ltd.
Origin
China
Production Capacity
2000kg/Month
Reference Price
$ 63.00 - 135.00
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Product Description

Heparin Sodium Powder Prevents Blood Embolism CAS: 9041-08-1 Anticoagulant Drugs
Heparin Sodium Powder Prevents Blood Embolism CAS: 9041-08-1 Anticoagulant Drugs
Heparin Sodium Powder Prevents Blood Embolism CAS: 9041-08-1 Anticoagulant Drugs
Product Name HEPARIN SODIUM
Appearance White to off- white powder
Residue on ignition 28.0%- 41.0%
Nitrogen(calculated on the dried basis ) 1.3%-2.5%
Heavy metals  ≤30ppm
Limit of galactosamine in total hexosamine ≤1%
Nucleotidic impurities Absorbance at 260nm: ≤0.20




Absence of oversulfated chondroitin sulfate 		A. Proceed as directed in identification test A. No features associated with oversulfated chondroitin sulfate are found between 2.12 and 3.00ppm

B. No peaks corresponding to oversulfated chondroitin sulfate should be detected eluting after the heparin peak.
PH 5.0-7.5
Loss on drying ≤5.0%
Protein impurities ≤1.0%
Bacterial endotoxins test Not more than 0.03 USPEU/USPU of Heparin
Not more than 0.03 USPEU/USPU of Heparin ≥180 IU/mg
Residual solvents Ethanol: ≤ 5000 ppm
Microbial contamination A:Total viable aerobic count: max 10CFU/g

B: Molds/yeasts

Description:

Reviparin sodium, a second-generation low molecular weight heparin produced from porcine mucosal heparin, has been introduced for the prevention of deep vein thrombosis and pulmonary embolism following surgery. It has sustained activity and increased bioavailability over unfractioned heparin. More noticeably, reviparin shows a pronounced inhibitory effect, both in vitro and in vivo , on smooth cell proliferation which plays a predominant role in restenosis following angioplasty. Indeed, a lower incidence of restenosis without major bleeding complications has been reported for reviparin treated patients who successfully underwent percutaneous transluminal coronary angioplasty.

Usage:

1. Biochemical studies; used for preventing the conversion of prothrombin into thrombin; has blood anti-thrombosis effect.
2. For the delay and prevention of blood clotting.
3. Heparin sodium salt is a mucopolysaccharides biochemical medicine extracted from porcine small intestinal mucosa with strong anticoagulant activity. Mclcan found it from the liver tissue of dog in the study of the clotting mechanism. Brinkous et al proved that heparin having anticoagulant activity. After the first application of heparin as an anticoagulant in clinical filed, it has drawn worldwide attention. With a strong anticoagulant effect, heparin is the primary choice for prevention and treatment of deep vein thrombosis and other thrombotic diseases.

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Pharmaceutical Intermediate

LEGALIS.IT, 2023