Manufacturer Supply High Quality CAS 479-18-5 Dyphylline

Model NO.
TY-79XQ
Colour
White
Assay
99%
Shelf
2 Years
Place
China
Package
Foil Bag
Transport Package
25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
Please contact us for quote
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Product Description

Manufacturer Supply High Quality CAS 479-18-5 Dyphylline
Manufacturer Supply High Quality CAS 479-18-5 Dyphylline

Manufacturer Supply High Quality CAS 479-18-5 Dyphylline
 
Product name Diprophylline
CAS 479-18-5
Appearance white powder
Assay 99%
Storage Cool and Protect from light


Manufacturer Supply High Quality CAS 479-18-5 Dyphylline
Diprophylline
Product Name Diprophylline

CAS 479-18-5

MF C10H14N4O4

MW 254.24

EINECS 207-526-1

MOL File 479-18-5.mol

Chemical Properties

Melting point 161-162 °C(lit.)
Boiling point 397.46°C (rough estimate)
Density  1.3036 (rough estimate)
refractive index  1.6200 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Freely soluble in water, slightly soluble in ethanol (96 per cent).
pka 13.74±0.20(Predicted)
form  Powder
color  White
Water Solubility  33 g/100 mL (25 ºC)
Merck  14,3479
BRN  284563
CAS DataBase Reference 479-18-5(CAS DataBase Reference)
NIST Chemistry Reference Dyphylline(479-18-5)
EPA Substance Registry System Dyphylline (479-18-5)

Manufacturer Supply High Quality CAS 479-18-5 Dyphylline
Usage And Synthesis
Description

Dyphylline is the N-7 dihydroxypropyl derivative of theophylline and is not a theophylline salt. Dyphylline does not get metabolized to theophylline in vivo, and even though it contains 70% theophylline by molecular weight ratio, the equivalent amount to theophylline is not known. Dosing must be accomplished independently by monitoring dyphylline blood levels. Dyphylline has a diminished bronchodilator effect compared to theophylline, but it may have lower and less serious side effects. Dosage forms available are an elixir and tablets.

Description

Dyphylline is a xanthine derivative that acts as an A1 and A2 adenosine receptor antagonist and phosphodiesterase inhibitor and exhibits bronchodilator and vasodilator effects. It also moderately inhibits microsomal prostaglandin E synthase-1 with an IC50 value of 200 μM and downregulates ABCG2 drug transporter expression in multidrug resistant tumor cells.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.

Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
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Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.

Manufacturer Supply High Quality CAS 479-18-5 Dyphylline Manufacturer Supply High Quality CAS 479-18-5 Dyphylline Manufacturer Supply High Quality CAS 479-18-5 Dyphylline Manufacturer Supply High Quality CAS 479-18-5 Dyphylline

 

Organic Intermediate

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